Author

Prakash Arullampalam

University of BernORCID 0000-0001-5725-2290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:cryo-EM· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Daniel J. Lerner· 2 shared John D. TranteriD· 2 shared Rajan SahiD· 2 shared Tarek Mohamed Abd El‐AziziD· 2 shared Yonghui ZhaoiD· 2 shared Abigail AjaneliD· 1 shared Adam BalutowskiiD· 1 shared Alice LiuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

Daniel J. Lerner

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3 papers

Recent·Most cited

Cell BiologyHypertensionPeer-reviewedFeb 4, 2026

Endothelial LRRC8C associates with LRRC8A and LRRC8B to regulate vascular reactivity and blood pressure

Qiujun Yu, Yonghui Zhao, Joshua M Maurer…·Rajan Sah

This study identifies LRRC8C as a non-redundant component of the endothelial LRRC8 complex that regulates vascular reactivity and blood pressure.

4 citationstop 1%

humanexperimental assay

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Cell BiologyBloodPeer-reviewedJun 20, 2025

LRRC8 complexes are adenosine nucleotide release channels regulating platelet activation and arterial thrombosis

John D. Tranter, Ryan T. Mikami, Ashutosh Kumar…·Rajan Sah

This study identifies LRRC8 complexes as ATP/ADP release channels in platelets that regulate thrombosis by modulating calcium and PI3K-AKT signaling through P2X1, P2Y1, and P2Y12 receptors.

12 citationstop 2%

mouseproteomics

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BiochemistryNature CommunicationsPeer-reviewedJan 19, 2025

Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4

Babatunde Ekundayo, Prakash Arullampalam, Christian E. Gerber…·Dongchun Ni

The paper identifies the binding site of small molecule inhibitors NBA and IBA in TRPM4 using cryo-EM and patch clamp experiments.

20 citationstop 1%

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