Asgerally T. Fazleabas

This study shows that PIEZO1 enhances decidualization by promoting BECN1-dependent autophagy in response to ECM stiffness and cell contraction.

This paper develops a bioelectronic sensor using an insect olfactory system to detect and classify endometriosis by analyzing volatile organic compounds from cell cultures.

This study uses spatial transcriptomics to identify increased epithelium-macrophage signaling in endometriotic lesions, highlighting a new role for Complement 3 in lesion inflammation.

This paper presents a single-cell RNA sequencing atlas of the human uterus, identifying 39 cell subtypes and proposing a consensus annotation system, while highlighting dynamic changes and potential progenitor cells across menstrual cycle phases.

This study shows YAP1 and WWTR1 are essential for decidualization and pregnancy in mice, with pdKO mice showing subfertility and altered gene expression.

This study investigates HMGA2 overexpression in myometrial cells, showing it induces a stem cell-like state and contributes to fibroid development through dedifferentiation and altered extracellular matrix pathways.

This study shows ARID1A maintains repressive H3.3 chromatin through interactions with CHD4 and ZMYND8, suppressing genes involved in cell motility and epithelial-to-mesenchymal transition in endometriotic cells.