Wei Yu

This study identifies MAB_2363 as a division-associated protein that contributes to intrinsic resistance and virulence in Mycobacterium abscessus by affecting cell division and antibiotic susceptibility.

The paper designs high-fidelity Cas13 variants with minimal collateral RNA degradation effects, validated in mammalian cells and transgenic mice.

The paper predicts meiosis-essential genes by analyzing dynamic proteomes from spermatogenesis-synchronized mice and validates four candidates using knockout models.