Author
Babraham InstituteORCID 0000-0001-6355-3057Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Lucie A.G. van Leeuwen, Silvia Casanova, Oisharja Rahman…·Hayley J. Sharpe
The paper develops FlyPer, a Drosophila H2O2 biosensor toolkit, to measure subcellular H2O2 dynamics in vivo, revealing tissue-specific redox patterns during development and stress.
Katie E. Mulholland, Maxime Bourguet, Nuo Cheng…·Hayley J. Sharpe
This paper shows that pervanadate induces oxidation, which activates SRC kinases by disrupting autoinhibition and altering SH2 domain phosphopeptide binding, revealing a redox-dependent mechanism for SRC activation.
Sara B. Cruz-Migoni, Kamallia Mohd Imran, Aysha Wahid…·Anne‐Gaëlle Borycki
The paper shows that cilia-mediated Hedgehog signaling regulates muscle stem cell quiescence and cell cycle progression by switching from repressive to active states during activation.