Author
Babraham InstituteORCID 0000-0001-6534-4435Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Lucie A.G. van Leeuwen, Silvia Casanova, Oisharja Rahman…·Hayley J. Sharpe
The paper develops FlyPer, a Drosophila H2O2 biosensor toolkit, to measure subcellular H2O2 dynamics in vivo, revealing tissue-specific redox patterns during development and stress.
Till Kallem, Yanyu Guo, Meghan K Reynolds…·Benjamin Thomas Goult
The paper shows that the A50I vinculin mutation is not talin-binding-null and that talin is essential for organizing vinculin tension gradients in focal adhesions.
Katie E. Mulholland, Maxime Bourguet, Nuo Cheng…·Hayley J. Sharpe
This paper shows that pervanadate induces oxidation, which activates SRC kinases by disrupting autoinhibition and altering SH2 domain phosphopeptide binding, revealing a redox-dependent mechanism for SRC activation.