Author

Christina Fotopoulou

Imperial College LondonORCID 0000-0001-6375-9645Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Paula CunneaiD· 2 shared Alex MontoyaiD· 1 shared Alexis R. BarriD· 1 shared Alizée J GrimmiD· 1 shared Anne I. Kraemer· 1 shared Aspram MinasyaniD· 1 shared Betheney R. PennycookiD· 1 shared Bhavik PateliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Paula CunneaORCID

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2 papers

Recent·Most cited

Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors

Carmen Ramírez-Moncayo, Restuadi Restuadi, Guanying Zhang, Daniel Marks, Paula Ortega-Prieto, Emily Doherty, Nathalie Lambie, Chad Whilding, Ivan Andrew, Alex Montoya, Bhavik Patel, Katie Tyson, Betheney R. Pennycook, Lauren Pendergast, Vincen Wu, , Louise Fets

The paper uses multimodal imaging to show that lysosomes act as a reservoir for PARP inhibitors, leading to heterogeneous drug distribution and response in ovarian cancer.

Nature Communications · Mar 17, 2026Peer-reviewedCancer Biology

Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer

Eleonora Ghisoni, Fabrizio Benedetti, Aspram Minasyan, Mathieu Desbuisson, Paula Cunnea, Alizée J Grimm, Noémie Fahr, Charlotte Capt, Nicolas Rayroux, Flavia De Carlo, D. C. Gulhan, Julien Dagher, David Barras, Matteo Morotti, Juan A. Marín‐Jiménez, , Denarda Dangaj Laniti

The paper identifies immune phenotypes and myeloid cell networks in recurrent ovarian cancer that influence prognosis and immune environment reinstatement.

Cancer Cell · Jul 31, 2025Peer-reviewedImmunology