Gerald J Larrouy-Maumus

This study identifies CysK2 as a copper-responsive metabolic effector in M. tuberculosis that links copper sensing to redox homeostasis and intracellular adaptation during infection.

This study shows that colistin resistance in K. pneumoniae modifies LPS, leading to different inflammatory responses in host cells.

This study identifies polymyxin B heteroresistance in Klebsiella oxytoca clinical isolates, showing a 16-fold resistance variation between subpopulations.

This study shows that rice plants increase DMA exudation under Zn deficiency, supporting its role as a general stress response, though Zn uptake does not increase.

This study identifies MenG inhibitors that restore bedaquiline susceptibility in resistant tuberculosis strains through menaquinone pathway disruption.

This study shows that Rv3400, a β-phosphoglucomutase in M. tuberculosis, is essential for trehalose metabolism, as its deletion increases β-D-glucose 1-phosphate and causes growth defects on trehalose.

This study shows that glutathione is essential for survival and recovery from long-term nitrogen starvation in E. coli by regulating Hfq condensate dynamics.

This study shows RfaH is essential for Yersinia pseudotuberculosis virulence and adaptation, as its loss reduces virulence and impairs persistent infection.

This study shows that polymyxin B lethality requires energy-dependent outer membrane disruption and depends on metabolic activity and LPS synthesis.

This study investigates the role of anemia and tissue hypoxia in hyperlactatemia during severe malaria using a murine model and human samples.

This paper engineers environmental bacteria to degrade PET plastic by enhancing PET bioavailability and secreting a high-activity hydrolase.

This paper identifies the metabolic flux partitioning between the TCA cycle, glyoxylate shunt, and reversible methyl citrate cycle in Mtb as critical for its nutritional flexibility when co-metabolizing carbon substrates.

The paper shows antibiotic resistance genes in E. coli exhibit dose-responsive expression under increasing antibiotic concentration, analogous to Ohm's law, and identifies mechanisms involving mRNA/protein variation and cell memory.