Julia Takuno Hespanhol

A widespread bacterial toxin reveals a deeply divergent DNase family neutralized by diverse immunity proteins.

This study identifies Rehh as a widespread bacterial toxin with DNase activity, revealing its evolutionary divergence and mechanism of neutralization by immunity proteins.

An RNase Toxin Hijacks Elongation Factor-Tu to Cleave the Ribosomal Sarcin-Ricin Loop

This paper characterizes SRLase1, an RNase toxin that cleaves the sarcin-ricin loop of 23S rRNA by repurposing EF-Tu, revealing a new mechanism of ribosome inhibition.

Genome-directed study reveals the diversity of Salmonella T6SS effectors and identifies a novel family of lipid-targeting antibacterial toxins

The paper identifies a novel family of lipid-targeting antibacterial toxins from Salmonella using in-silico analysis of genomes and biochemical characterization.