Author

Ziwei Zhang

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Genomics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

David KlenermaniD· 2 shared Shekhar KediaiD· 2 shared Alexander GuseviD· 1 shared Annelies QuaegebeuriD· 1 shared Bidesh MahataiD· 1 shared Bing Li· 1 shared Christopher J. Ward· 1 shared Daniel F. HeraghtyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

David KlenermanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Early synaptic pathology is associated with small tau aggregates in Alzheimer's disease

Emre Fertan, Shekhar Kedia, George Nolan, Georg Meisl, Matthew W. Cotton, Karin H. Müller, Ziwei Zhang, Leila Mureşan, Annelies Quaegebeur, Maria Grazia Spillantini, David Klenerman

The paper examines tau aggregates in Alzheimer's disease synaptosomes, finding that small tau aggregates are associated with early synaptic pathology.

Acta Neuropathologica · Jan 23, 2026Peer-reviewedNeuroscience

Hyaluronidase unlocks sequestered CEACAM5 and improves CAR T-cell therapy in colorectal cancer

Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel F. Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman

This study shows that hyaluronidase improves CEACAM5 accessibility on colorectal cancer cells, enhancing CAR T-cell therapy effectiveness by reducing glycocalyx thickness and restoring sustained T-cell activation.

Advanced Science · Jan 22, 2026Peer-reviewedImmunology

Circulating chromatin reveals the effects of disease-associated variants on gene regulation

Ziwei Zhang, Surya B. Chhetri, Karl Semaan, Ze Zhang, Zhenjie Jin, Shahabeddin Sotudian, Liming Liang, Alexander Gusev, Sylvan C. Baca

The paper identifies cell-free chromatin QTLs (cfcQTLs) from cancer patients' blood to uncover regulatory effects of genetic variants across diverse tissues and diseases.

bioRxiv · Nov 12, 2025 · PreprintGenomics