X. Lucas Lu

This study identifies decorin-mediated extracellular matrix stabilization as a key factor in maintaining cartilage integrity during aging, showing its role in preventing age-associated osteoarthritis.

This study shows decorin strengthens collagen II-aggrecan integration in cartilage matrix, reducing aggrecan loss and supporting its therapeutic potential for osteoarthritis.

This paper introduces a click chemistry-based method to quantify ECM turnover, validated for drug screening and regenerative medicine applications.

This study investigates the structure-mechanical properties and mechanobiological functions of the pericellular matrix in fibrocartilage, highlighting the critical role of collagen V in maintaining its integrity and function.