Biao Han

This study identifies decorin-mediated extracellular matrix stabilization as a key factor in maintaining cartilage integrity during aging, showing its role in preventing age-associated osteoarthritis.

This study shows decorin strengthens collagen II-aggrecan integration in cartilage matrix, reducing aggrecan loss and supporting its therapeutic potential for osteoarthritis.

This study shows primary cilia regulate postnatal articular cartilage organization by coordinating Indian Hedgehog signaling and mechanical load responses, affecting tidemark patterning and matrix composition.