Author

Thomas Li

Drexel UniversityORCID 0000-0002-4207-4652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Lin Han BiD· 3 shared David E. BirkiD· 2 shared Mingyue FaniD· 2 shared Robert L. MauckiD· 2 shared X. Lucas LuiD· 2 shared Yuchen LiuiD· 2 shared Annie PorteriD· 1 shared Benjamin I. Binder‐MarkeyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBioengineering

Lin Han BORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Decorin promotes nascent proteoglycan retention in cartilage matrix by strengthening collagen II-aggrecan integration

Thomas Li, Gabriela Canziani, Yuchen Liu, Neil Patel, Biao Han, Mingyue Fan, Annie Porter, Bryan Kwok, Chao Wang, Qing Li, David E. Birk, Renato V. Iozzo, IRWIN M. CHAIKEN, X. Lucas Lu, Robert L. Mauck, Lin Han B

This study shows decorin strengthens collagen II-aggrecan integration in cartilage matrix, reducing aggrecan loss and supporting its therapeutic potential for osteoarthritis.

Acta Biomaterialia · Jun 9, 2026Peer-reviewedBiophysics

Structure-Mechanics Principles and Mechanobiology of Fibrocartilage Pericellular Matrix: A Pivotal Role of Type V Collagen

Chao Wang, Mingyue Fan, Su‐Jin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han

This study investigates the structure-mechanical properties and mechanobiological functions of the pericellular matrix in fibrocartilage, highlighting the critical role of collagen V in maintaining its integrity and function.

Advanced Science · May 23, 2025Peer-reviewedBioengineering

Effects of injury size on local and systemic immune cell dynamics in volumetric muscle loss

Ricardo C. Whitaker, Samuel Sung, Tina Tylek, Gregory E. Risser, Erin M. O’Brien, Phoebe Ellin Chua, Thomas Li, Ryan J. Petrie, Lin Han, Benjamin I. Binder‐Markey, Kara L. Spiller

This study examines how injury size affects immune cell dynamics in muscle repair, finding early macrophage dysfunction and increased neutrophils in fibrotic outcomes.

npj Regenerative Medicine · Feb 12, 2025Peer-reviewedBioengineering