Author

Huaxi Xu

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0001-7031-7853Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Huaxi Xu1 paper

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Lu-Lin JiangiD· 2 shared Amberlene J. De La RochaiD· 1 shared Angus Clark NairniD· 1 shared Anthony Daggett· 1 shared C.Y. Daniel LeeiD· 1 shared Denghong ZhangiD· 1 shared Eitan WongiD· 1 shared Fuying GaoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Lu-Lin JiangORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 3, 2023

BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice

C.Y. Daniel Lee, Amberlene J. De La Rocha, Kellie Inouye…·X. William Yang

This study shows that TREM2-R47H reduces amyloid plaques but fails to improve cognitive deficits or microglial reactivity in 5xFAD mice.

1 citation

mouseexperimental assay

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NeuroscienceJournal of NeurosciencePeer-reviewedAug 9, 2022

Downregulating PTBP1 fails to convert astrocytes into hippocampal neurons and to alleviate symptoms in Alzheimer's mouse models

Tiantian Guo, Xinjia Pan, Guangtong Jiang…·Yingjun Zhao

This study shows that reducing PTBP1 in astrocytes does not convert them into neurons or improve Alzheimer's symptoms in mouse models.

37 citations

mouseexperimental assay

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NeuroscienceThe Journal of Experimental MedicinePeer-reviewedMay 27, 2021

GSAP regulates mitochondrial function through the Mitochondria-associated ER membrane in the pathogenesis of Alzheimer's disease

Peng Xu, Jerry C. Chang, Xiaopu Zhou…·Paul Greengard

This study identifies GSAP's role in Alzheimer's disease by showing it regulates mitochondrial function through the MAM and lipid homeostasis, with a SNP linked to increased AD risk.

33 citations

mousebulk RNA-seq

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