Cathy Fernandes

This study shows that adult social isolation in mice increases miR-30e-5p expression in the hippocampus, reduces its target gene Neurod1, and impairs pattern separation without affecting anxiety or depression-like behaviors.

The paper identifies cardiotonic steroids as potential repurposing candidates for lithium treatment of severe depression based on transcriptional and epidemiological analyses.

This study shows that KDM5B deficiency in mice leads to autism-like behaviors and increased brain size, which can be mitigated by NMDAR antagonists.

The paper identifies sex-specific social deficits in Cntnap2 KO mice, linked to reduced synaptic density and increased microglial activity in males.

This study shows that psychosocial stress delays puberty and increases anxiety in female mice by affecting Urocortin3 neurons in the medial amygdala.

This study investigates the effects of CHD8 mutations on brain development in mice, finding non-linear gene expression and growth changes depending on mutation severity.

This study examines Chd8 haploinsufficient mice, finding brain overgrowth, altered gene expression, and functional connectivity changes linked to autism-like features.