Cyril Cros

The paper maps a whole-body single-cell transcriptome into an electron microscopy volume of an annelid worm to study cellular morphology and gene regulation.

The paper integrates bulk and single-cell RNA-seq data from C. elegans neurons to improve transcript detection and differential gene analysis.

The paper creates a comprehensive neurotransmitter atlas in C. elegans by analyzing CRISPR/Cas9 knock-in reporter strains, revealing new expression sites and co-expression patterns.

The paper investigates the role of homeobox genes in neuronal identity specification in C. elegans, finding that 111 of 118 neuron classes require homeobox genes for proper differentiation.

The paper shows that homeobox genes control neuronal subtype identities in C. elegans by acting as toggle switches to differentiate between closely related neuron classes.

The paper integrates bulk and single-cell RNA-seq data from C. elegans neurons to improve transcript detection and differential gene analysis.

The paper provides a comprehensive gene expression profile of all 302 neurons in the C. elegans nervous system and identifies cis-regulatory elements and adhesion proteins involved in synaptic specificity.

Transcriptomes of 52,412 neurons resolve 109 of the 118 canonical hermaphrodite neuron classes, and neuropeptide genes separate subtypes inside individual classes.