Janine Gote-Schniering

This study maps venous remodelling in IPF using multiscale imaging and molecular data, showing venous enlargement correlates with disease severity and poor survival.

This study uses single-cell and spatial transcriptomics to identify structural cell circuits in BOS lungs and their spatial organization during airway obliteration.

This study shows that local IFNγ signaling in aged lungs impairs alveolar progenitor cell regeneration, and reducing IFNγ levels restores regenerative capacity.

This study shows that deleting p16INK4a or targeting p16+ cells reverses alveolar epithelial dysfunction and promotes lung regeneration in emphysema.

The paper uses single-cell RNA-seq to analyze aging effects on lung regeneration, identifying immune cell states linked to impaired progenitor function in aged mice.

The paper uses radioproteomics to stratify molecular response to antifibrotic treatment in pulmonary fibrosis by analyzing radiomic and proteomic profiles in mice and patients.

This study uses single-cell RNA-sequencing to analyze how different nanomaterials affect lung inflammation in mice, identifying cell type-specific responses and mechanisms.

The paper introduces scDVP, a spatial single-cell proteomics method, and finds that half of the murine hepatocyte proteome varies spatially within liver tissue.

CellRank maps cell fates in single-cell RNA sequencing data by integrating RNA velocity and trajectory inference, revealing novel regeneration trajectories in lung injury.