Author

Gowtham Boosarpu

Philipps University of Marburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mareike LehmanniD· 3 shared Carina Steinchen· 2 shared Janine Gote-SchnieringiD· 2 shared M. Camila Melo-NarváeziD· 2 shared Mélanie KönigshoffiD· 2 shared Qianjiang HuiD· 2 shared Ali Önder YildirimiD· 1 shared Amine Chahin· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

Mareike LehmannORCID

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3 papers

Recent·Most cited

Lifespan Analysis of the Lung Epithelium Reveals Inflammatory Reprogramming and Regenerative Decline

Gowtham Boosarpu, Eva M. Guenther, Carina Steinchen, M.C. Melo Narvaez, Camille Barro, Turgud Nazarli, Antonia Müller, Francesco Campi, Friso F Bratzel, Laura-Marie Twardowski, Qianjiang Hu, Efthymios Fousekis-Papakonstantinou, Roxana Maria Wasnick, Hosam Shams-Eldin, Anne Hilgendorff, , Mareike Lehmann

This study analyzes lung epithelial cells across the lifespan in mice, identifying age-related declines in regeneration linked to inflammation and epigenetic changes.

bioRxiv · Jun 4, 2026 · PreprintCell Biology

Local IFNγ signaling contributes to the regenerative decline of aged alveolar progenitor cells

Jake Jensen, Kai Guo, Janine Gote-Schniering, Meeta Mistry, Zane Orinska, Jia-qi Wang, M. Camila Melo-Narváez, Gowtham Boosarpu, Amine Chahin, Margherita Paschini, Madison Seymour, Patrizia Pessina, Susanna M. Dang, Qianjiang Hu, Shannan Ho Sui, , Carla F. Kim

This study shows that local IFNγ signaling in aged lungs impairs alveolar progenitor cell regeneration, and reducing IFNγ levels restores regenerative capacity.

bioRxiv · Apr 9, 2026 · PreprintCell Biology

Single cell decomposition of multicellular aging programs associated with impaired lung regeneration

Janine Gote-Schniering, M. Camila Melo-Narváez, Gowtham Boosarpu, David Lauer, Sai Rama Sridatta Prakki, Huijuan Wang, Matthias Brunner, Simrah Khan, Meshal Ansari, Michael Ammeter, Eshita Jain, Nikola Puda, Konstantin Wiedemann, Carina Steinchen, Sara Ashgapour, , Herbert B. Schiller

The paper uses single-cell RNA-seq to analyze aging effects on lung regeneration, identifying immune cell states linked to impaired progenitor function in aged mice.

bioRxiv · Jul 24, 2025 · PreprintCell Biology