This study identifies TAOK1 as a regulator of replication fork stability in BRCA1/2-deficient tumors, showing it enhances sensitivity to PARPi and IR through PCNA and ISG15 interactions.

DOI 10.1101/2025.10.14.682031

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintJul 2, 2025

Anthrax toxin receptor 2 is the Receptor for Clostridium perfringens NetF: Structural Insights into Toxin Binding and Pore Formation

Chang Wang, Filippo Cattalani, Ioan Iacovache…·Benoît Zuber

This study identifies ANTXR2 as the receptor for C. perfringens NetF toxin, revealing structural insights into its binding mechanism and pore formation.

DOI 10.1101/2025.07.02.662835

structural biologyexperimental assay

𝕏 PostBluesky

ZoologyMedical and Veterinary EntomologyPeer-reviewedMar 7, 2025

Preimaginal development of Aedes aegypti in brackish water produces adult mosquitoes with thicker cuticles and greater insecticide resistance

Kokila Sivabalakrishnan, Andrew Frederick Hemphill, S.H.P.P. Karunaratne…·Ranjan Ramasamy

This study shows that Aedes aegypti mosquitoes developing in brackish water have thicker cuticles and higher insecticide resistance compared to those developing in fresh water.

8 citations

Arabidopsisexperimental assay

𝕏 PostBluesky