Author

Paul A. Beare

National Institutes of HealthORCID 0000-0002-2282-177XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:host-pathogen & immune response· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:multiple species· 1

Frequent Co-Authors

Craig MartensiD· 3 shared Aaron CarmodyiD· 2 shared Adam HageiD· 2 shared Justin LackiD· 2 shared Mikhaila Janes· 2 shared Sonja M. BestiD· 2 shared Suhyeon Yoon· 2 shared Tovah E. MarkowitziD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Craig MartensORCID

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Author profile →

3 papers

Recent·Most cited

A Synthetic Consensus Chiroptera IFN-β Induces IFN-I Signaling Across Diverse Bat Taxa

Julianne Bullock, Brown Bulloch, Anthony McBain, Tom Hill, Aaron Carmody, Yi He, Lucas De Sousa Paula, Paul A. Beare, Craig Martens, Arthur Wickenhagen, Sarah van Tol

The paper designs a synthetic consensus IFN-β for bats that induces IFN-I signaling across diverse bat species, enabling study of antiviral immunity.

bioRxiv · Oct 29, 2026 · PreprintImmunology

Epigenetic regulation of DPP4 receptor expression by NONO enables replication of MERS-CoV

Adam Hage, Mikhaila Janes, Seth D. Scott, Suhyeon Yoon, Kevin Rose, Tovah E. Markowitz, Lara M. Myers, Aaron Carmody, Lenny Triem, Olivia Straw, Kristin L. McNally, Paul A. Beare, Justin Lack, Craig Martens, Sonja M. Best

This study identifies NONO as a host factor that epigenetically regulates DPP4 expression, facilitating MERS-CoV replication by modulating histone modifications at the DPP4 locus.

bioRxiv · Sep 23, 2026 · PreprintMicrobiology

The paraspeckle protein NONO potentiates the antiviral innate immune response through chromatin regulation

Adam Hage, Mikhaila Janes, Byron Shue, Tovah E. Markowitz, Suhyeon Yoon, Jeffrey G. Shannon, Paul A. Beare, Rebecca M. Broeckel, Justin Lack, Craig Martens, Sonja M. Best

This study identifies NONO as a critical facilitator of antiviral innate immune response by promoting chromatin accessibility and IFN-I/ISG expression.

bioRxiv · Jul 14, 2026 · PreprintImmunology