Kyla D. Mace

Sensory-sleep dysfunction is a shared phenotype across genetically distinct neurodevelopmental disorder models

The paper examines how sensory input interacts with sleep regulation in three genetically distinct neurodevelopmental disorder models and identifies impaired sensory-sleep integration as a shared phenotype.

Cross-trait clustering of sub-threshold sleep genetic signals identifies EGR2 as a conserved regulator of sleep

The paper identifies EGR2 as a conserved sleep regulator by analyzing sub-threshold genetic signals across sleep-related traits in multiple species.

Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2

The paper identifies beat-Ia/CADM2 as a gene involved in hypersomnia by showing its role in sleep regulation across species and demonstrates potential therapeutic targets.

Learning from unexpected events in the neocortical microcircuit

The paper shows that cortical pyramidal neurons exhibit distinct unexpected event signals in somata and distal apical dendrites that change over days, suggesting a role in hierarchical computation.

Differential encoding of temporal context and expectation under representational drift across hierarchically connected areas

The paper shows that visual areas differentially encode temporal context and expectation in natural scenes, with representational drift observed in lower areas but not higher ones.

Stimulus novelty uncovers coding diversity in survey of visual cortex

The paper identifies diverse functional neuron types in the visual cortex that process novel and familiar stimuli in mice.

A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex

The paper maps brain-wide monosynaptic inputs to specific neuron classes in mouse visual cortex using an improved rabies virus tracing strategy and identifies connectivity patterns within and between visual areas.

A standardized non-visual behavioral event is broadcasted homogeneously across cortical visual areas without modulating visual responses

The paper investigates how a standardized non-visual motor behavior is represented in visual cortex areas and finds it elicits consistent neural responses independent of visual processing.

Measuring stimulus-evoked neurophysiological differentiation in distinct populations of neurons in mouse visual cortex

The paper measures stimulus-evoked neurophysiological differentiation in mouse visual cortex neurons across layers and areas, finding greater differentiation in specific layers and areas for unscrambled stimuli.

A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas

The paper presents a dataset and analysis of spiking activity across multiple mouse visual areas, revealing that functional connectivity mirrors anatomical hierarchy.

Experience shapes activity dynamics and stimulus coding of VIP inhibitory and excitatory cells in visual cortex

The paper examines how visual experience affects activity dynamics and stimulus coding in excitatory and VIP inhibitory cells in mouse visual cortex during a change detection task.

Similar visual perception in GCaMP6 transgenic mice despite differences in learning and motivation

The paper compares perceptual decisions across GCaMP6 transgenic mice during a visual task, finding high correlation despite differences in learning and motivation.

A large-scale, standardized physiological survey reveals higher order coding throughout the mouse visual cortex

The paper presents a large-scale dataset of neural activity in the mouse visual cortex and shows that responses to different stimuli are largely independent, suggesting multi-layer hierarchical computation.