Author

Chenicka Lyn Mangahas

Centre Hospitalier Universitaire Sainte-Justine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

C. Casini RaggiiD· 2 shared Gaël Moquin‐BeaudryiD· 2 shared Marie-Agnès M’Callum· 2 shared Massimiliano PaganelliiD· 2 shared Nissan Baratang· 2 shared Quang Toan Pham· 2 shared Silvia Selleri· 2 shared Anne Aumont· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

C. Casini RaggiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Off-the-Shelf Engineered Liver Tissue Reverses Acute Liver Failure Without Immunosuppression

C. Casini Raggi, Pascal Lapierre, Marie-Agnès M’Callum, Quang Toan Pham, Silvia Selleri, Radu Alexandru Paun, Nissan Baratang, Chenicka Lyn Mangahas, Basma Benabdallah, Gaël Moquin‐Beaudry, Jiwoon Park, Dorothée Bouron Dal Soglio, Yves Théorêt, Robert E. Schwartz, Christian M. Beausejour, , Massimiliano Paganelli

This paper describes engineered liver tissue that reverses acute liver failure in mice without immunosuppression, demonstrating potential for clinical translation.

bioRxiv · Oct 8, 2025 · PreprintBioengineering

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models

Paule E. H. M’Bra, Laura K. Hamilton, Gaël Moquin‐Beaudry, Myriam Aubin, Chenicka Lyn Mangahas, Federico Pratesi, Elsa Brunet‐Ratnasingham, Anne Castonguay, Sophia Mailloux, Manon Galoppin, Megan Bernier, Marta Turri, Annick Vachon, Marian Mayhue, Anne Aumont, , Karl J. L. Fernandes

This study shows that two ketogenic diets improve cognition and metabolic health in Alzheimer's disease mouse models, with distinct effects on peripheral metabolism.

bioRxiv · Sep 4, 2024 · PreprintNeuroscience

Leveraging complex interactions between signaling pathways involved in liver development to robustly improve the maturity and yield of pluripotent stem cell-derived hepatocytes

C. Casini Raggi, Marie-Agnès M’Callum, Quang Toan Pham, Perrine Gaub, Silvia Selleri, Nissan Baratang, Chenicka Lyn Mangahas, Gaël Cagnone, Bruno Reversade, Jean‐Sébastien Joyal, Massimiliano Paganelli

bioRxiv · Sep 2, 2020 · PreprintDevelopmental Biology