Amanda M. Casto

The paper reports a case of HSV mistyping caused by HSV-1 x HSV-2 recombination in the UL27 gene, which is important for diagnostics and therapeutics.

The paper characterizes antiviral resistance in HSV-1 from a DOCK8-deficient patient using phenotypic and genotypic methods, finding genotypic testing more effective and documenting rapid intrahost HSV-1 evolution.

This study uses real-time metagenomic sequencing during a norovirus outbreak to identify transmission clusters and ongoing viral shedding in a hospital setting.

This study identifies interspecies recombination events in HSV-2 genomes and shows their impact on genetic variation and T-cell recognition.

The paper develops tools to directly sequence HSV genomes from clinical samples with high sensitivity and low viral load, revealing limited evolution during cell culture.