Nicole A. P. Lieberman

This study analyzes Treponema pallidum strains in Buenos Aires, Argentina, using whole genome sequencing and tprK locus analysis to understand transmission dynamics and lineage-specific diversity.

The paper shows three T. pallidum isolates with Tp0705 PBP polymorphisms are equally susceptible to penicillin G and ceftriaxone.

The paper introduces genetically encoded fluorescent tags for Treponema pallidum and Sf1Ep cells to enhance visualization and study host-pathogen interactions in syphilis research.

This study shows that long-term in vitro exposure of Treponema pallidum to sub-bactericidal doxycycline does not induce resistance, supporting the use of doxy-PEP for syphilis prevention.

The paper identifies Tp-specific CD4+ T cell responses in blood and skin of syphilis patients, showing persistence after treatment and highlighting potential vaccine targets.

The paper analyzes Treponema pallidum genomic data from Seattle to identify strain circulation and tprK antigen variation patterns in syphilis cases.