Author
Washington University in St. LouisORCID 0000-0001-8476-6246Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Patrick W. Sheehan, Stuart B. Fass, Darshan Sapkota…·Erik S. Musiek
The paper identifies cell-type and disease-specific circadian gene expression changes in glial cells under amyloid pathology or aging in mice.
Henry C Hollis, Ashish Sharma, Patrick W. Sheehan…·Ron C. Anafi
The paper estimates circadian phases in human brain cells using single-nucleus RNA sequencing and finds disrupted ribosomal rhythms in Alzheimer's patients.
Nicholas J. Constantino, Caitlin M. Carroll, Holden C. Williams…·Shannon L. Macauley
This study shows that Kir6.2-KATP channels regulate glycolytic flux, neuronal activity, and sleep-wake transitions by modulating lactate dynamics and metabolic stability.
Percy Y. Griffin, Patrick W. Sheehan, Julie M. Dimitry…·Erik S. Musiek
This study shows that the BMAL1-REV-ERB axis regulates complement expression and microglial synaptic phagocytosis in the hippocampus, with diurnal variation observed in wild-type mice.
Brian V. Lananna, Collin J. Nadarajah, Mariko Izumo…·Erik S. Musiek
This study shows BMAL1 regulates astrocyte activation and function through cell-autonomous and non-cell-autonomous mechanisms, impacting neuronal survival and brain health.