Tanmay P. Lele

This study identifies α6β4 integrins as initiators of epithelial eversion and shows that increased cell proliferation and anchorage-independence sustain apical-out polarity.

The paper investigates how cancer cells adapt to soft extracellular matrix by analyzing multi-omics data to identify molecular mechanisms underlying fitness differences.

This study shows that nuclear mechanics influence intestinal stem cell differentiation by sensing tissue shape and modulating lamin-A levels.

This study identifies a dynamic nuclear-plasma membrane contact mediated by the LINC complex that maintains epithelial architecture through Src signaling.

The paper shows that changes in GTP availability, caused by cellular processes like migration, affect nucleocytoplasmic transport rates, impacting RNA export and protein synthesis.

This study identifies a mechanism by which Escherichia coli tolerate antibiotics through dynamic porin inhibition, independent of gene expression, involving electrostatic modifications.