Ana Mendanha Falcão

The paper performs multi-omics analysis of choroid plexus across development in mice and rats, identifying cellular remodeling, immune gene activation, and a novel epithelial subtype.

This study identifies Gsta4 as a regulator of apoptosis in adult oligodendrocyte differentiation and remyelination, showing its role in modulating the Fas/Casp8/Bid mitochondrial axis.

This study identifies a primed chromatin state in oligodendroglia that facilitates rapid activation of immune gene programs in multiple sclerosis.

This study shows that PADI2-mediated citrullination is essential for oligodendrocyte differentiation, myelination, and motor function, with implications for remyelination therapies.

The paper uses single-cell transcriptomics to show that embryonic Pdgfra+ cells give rise to OPCs with convergent transcriptional profiles in different CNS regions.