Masayuki Kuraoka

The paper investigates whether genetically diverse B-cell receptor responses in simian-HIV infected macaques converge functionally, finding that functional convergence does not require genetic convergence.

This study shows that mitochondrial apoptosis limits non-proliferating and defective B cell states in germinal centers without affecting affinity maturation.

The paper shows that passive antibody feedback reduces RBS-specific GC B cells and increases unspecific B cells, with no effect on primary GC response magnitude.

The paper designs immunogens that redirect immune responses to a conserved influenza epitope using iterative machine learning and in vivo testing.

The paper develops fluorescence-barcoded cell lines expressing membrane-anchored influenza neuraminidases to study antibody responses and vaccine efficacy.