Author

Dirk Dietrich

University Hospital BonnORCID 0000-0002-4307-2448Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Susanne SchochiD· 4 shared Albert J. BeckeriD· 3 shared Julika PitschiD· 3 shared Anne QuatraccioniiD· 2 shared Johannes Alexander MülleriD· 2 shared Jonathan S. MarviniD· 2 shared Karen M. J. van LooiD· 2 shared Kaspar PodgorskiiD· 2 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Susanne SchochORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ste20-like kinase is critical for inhibitory synapse maintenance and its deficiency confers a developmental dendritopathy

Susanne Schoch, Anne Quatraccioni, Barbara K. Robens, Robert Maresch, Karen M. J. van Loo, Silvia Cases‐Cunillera, Tony Kelly, Thoralf Opitz, Valeri Borger, Dirk Dietrich, Julika Pitsch, Heinz Beck, Albert J. Becker

This study identifies SLK as critical for dendritic complexity and inhibitory synapse maintenance in neurons, with implications for human cortical malformations.

Journal of Neuroscience · Aug 16, 2021Peer-reviewedNeuroscience

Heterogeneity and excitability of BRAFV600E-induced tumors is determined by PI3K/mTOR-signaling state and Trp53-loss

Silvia Cases‐Cunillera, Karen M. J. van Loo, Julika Pitsch, Anne Quatraccioni, Sugirthan Sivalingam, Paolo Salomoni, Dirk Dietrich, Susanne Schoch, Albert J. Becker

This study identifies how PI3K/mTOR signaling and Trp53 loss determine the heterogeneity and excitability of BRAFV600E-induced brain tumors in mice.

bioRxiv · Feb 22, 2021 · PreprintNeuroscience

Optical analysis of the action range of glutamate in the neuropil

Elizabeth A. Matthews, Wenjing Sun, Shane M. McMahon, Michael Doengi, L. Halka, Stefanie Anders, Johannes Alexander Müller, Pia Steinlein, Natascha Vana, G. van Dyk, Julika Pitsch, Albert J. Becker, Alexander Pfeifer, Ege T. Kavalali, Alf Lamprecht, , Dirk Dietrich

The paper investigates glutamate spread in the neuropil using optical reporters and finds that glutamate can activate AMPA and NMDA receptors at distances up to 2 micrometers from the release site.

bioRxiv · Feb 5, 2021 · PreprintNeuroscience

A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies

Philip M. Borden, Peng Zhang, Amol V. Shivange, Jonathan S. Marvin, Joseph Cichon, Chuntao Dan, Kaspar Podgorski, António Manuel Pereira De Figueiredo, Ondřej Novák, Masashi Tanimoto, Eiji Shigetomi, Mark A. Lobas, Hyun-Tae Kim, Paula K. Zhu, Yajun Zhang, , Loren L. Looger

iAChSnFR, a fluorescent indicator built from a bacterial periplasmic binding protein, reports acetylcholine with large, fast signals in mouse, fish, fly and worm preparations.

bioRxiv · Feb 7, 2020 · PreprintNeuroscience

Stability, affinity and chromatic variants of the glutamate sensor iGluSnFR

Jonathan S. Marvin, Benjamin Scholl, Daniel E. Wilson, Kaspar Podgorski, Abbas Kazemipour, Johannes Alexander Müller, Susanne Schoch, Francisco José Urra Quiroz, Nelson Rebola, Huan Bao, Justin P. Little, Ariana N. Tkachuk, Edward Cai, Adam W. Hantman, Samuel S.‐H. Wang, , Loren L. Looger

The paper introduces variants of the glutamate sensor iGluSnFR with improved brightness, broader concentration detection, and different emission colors for enhanced in vivo imaging.

Nature Methods · Oct 19, 2018Peer-reviewedNeuroscience