David Drew

The paper reports the cryo-EM structure of Pseudomonas aeruginosa LysP bound to lysine and a nanobody, revealing its transport mechanism and inhibition by L-4-thialysine.

The paper investigates how cardiolipin interacts with membrane proteins to stabilize them, using a model protein and simulations to identify key factors.

This study uses a CRISPR homing screen to identify essential genes for malaria transmission in mosquito stages, finding a chloroquine resistance transporter-like protein critical for oocyst development.

The paper reports the cryo-EM structure of a TRAP transporter and elucidates its mechanism of sodium-driven substrate uptake.