A CRISPR homing screen finds a chloroquine resistance transporter-like protein of the Plasmodium oocyst essential for mosquito transmission of malaria
Arjun Balakrishnan, Mirjam Hunziker, Puja Tiwary, Vikash Pandey, David Drew, Oliver Billker
This study uses a CRISPR homing screen to identify essential genes for malaria transmission in mosquito stages, finding a chloroquine resistance transporter-like protein critical for oocyst development.
Nature Communications · Apr 24, 2025Peer-reviewedMicrobiology