Non-canonical enhancers control gene expression and cell fate in human pluripotent stem cells
Yang Cao, Oleksandr Dovgusha, Ayyub Ebrahımı, Stephen Bevan, Lukas Widmer, Fereshteh Torabi, Julia Kurlovich, Ignacio Rodríguez-Polo, Soumen Khan, Manthan Patel, Madapura M. Pradeepa, Ufuk Günesdogan, Stefan Schoenfelder
The paper identifies non-canonical enhancers in human pluripotent stem cells that lack typical enhancer features but regulate gene expression and cell fate.
bioRxiv · Jun 1, 2025 · PreprintGenomics