John A. Buglino

This study shows that ligand binding inhibits dimerization of the bacterial histidine kinase PdtaS, thereby repressing its activity and multi-ligand sensing.

This study investigates itaconate's role in human macrophages, showing distinct effects in alveolar-like and M-CSF-derived macrophages during M. tuberculosis infection.

This study identifies effluxosomes as dynamic membrane structures in M. tuberculosis that coordinate multi-metal resistance through PacL proteins and P-ATPase pumps.

This study shows that M. tuberculosis uses chalkophores to maintain respiration under copper limitation, which is critical for its virulence in mice.