Author

Madeline R. Luth

University of California San DiegoORCID 0000-0001-9059-1200Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Organism:plant (other)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Elizabeth A. WinzeleriD· 3 shared Cindy Smidt· 2 shared Francisco‐Javier GamoiD· 2 shared Julian C. RayneriD· 2 shared Krypton CarolinoiD· 2 shared Lee MiD· 2 shared Mukul RawatiD· 2 shared Oliver BillkeriD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Elizabeth A. WinzelerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedNov 24, 2025

Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials

Mukul Rawat, Nonlawat Boonyalai, Cindy Smidt…·Lee M

This paper identifies targets of dual-active antimalarials by evolving resistance to nine compounds and validates them using CRISPR and molecular docking.

DOI 10.1128/mbio.02423-25

experimental assaystatistical model

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 27, 2024

A novel chemogenomic screening platform for scalable antimalarial drug target identification

Christopher Bower-Lepts, Mukul Rawat, William Collins Keith…·Julian C. Rayner

This paper develops a chemogenomic platform using Plasmodium berghei artificial chromosomes to identify antimalarial drug targets through barcode sequencing and validation in Plasmodium falciparum.

4 citations

plant (other)bulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintFeb 17, 2021

Defining the Yeast Resistome through in vitro Evolution and Whole Genome Sequencing

Sabine Ottilie, Madeline R. Luth, Erich Hellemann…·Elizabeth A. Winzeler

The paper identifies genetic determinants of chemical resistance in yeast using in vitro evolution and whole genome sequencing, revealing key transcription factors involved in drug resistance.

4 citations

yeastwhole-genome sequencing

𝕏 PostBluesky