Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials
Mukul Rawat, Nonlawat Boonyalai, Cindy Smidt, Madeline R. Luth, Daisy Chen, Andrew Plater, John M. Post, De Lin, Joel McMillan, T.C. Eadsforth, Sonia Moliner Cubel, Oliver Billker, Julian C. Rayner, Francisco‐Javier Gamo, Beatriz Baragaña, , Lee M
This paper identifies targets of dual-active antimalarials by evolving resistance to nine compounds and validates them using CRISPR and molecular docking.
mBio · Nov 24, 2025Peer-reviewedMicrobiology