Benjamin E. Housden

This paper identifies AZT as a potential therapeutic for NF1 tumors through cross-species genetic analysis and validates its efficacy in human and mouse models.

The paper introduces three improved variants of the VDA method for genetic assays in Drosophila cells, enhancing throughput and sensitivity for drug target identification.

The paper introduces mVDA, a method for scalable genetic interaction screening in Drosophila cells, enabling genome-wide analysis by deconvolving phenotypes from multiple gene inhibitions.

This study shows that subpopulations of stationary phase bacteria resist antimicrobial peptides through enhanced efflux and other mechanisms, and suggests combining tachyplesin with sertraline to combat resistance.

The paper identifies and validates the RNAi pathway in Paramecium bursaria, showing its role in feeding-induced gene knock-down and endosymbiosis genetics.

The paper shows Notch signaling regulates ommatidial rotation in Drosophila by upregulating argos, an EGFR ligand, through direct transcriptional control in R4 photoreceptors.

The paper identifies genes involved in zinc detoxification in Drosophila cells through functional genomics and transcriptomics analyses, revealing key pathways and human disease-related gene orthologs.