Clara Taffoni

The paper identifies DNA-PKcs as a regulator of cyclic dinucleotide signaling, showing it interacts with CDN and modulates STING activation and antiviral responses.

This study shows that MECP2 inhibits cGAS signaling by exporting to the cytosol upon dsDNA detection, dampening inflammation and antiviral responses.

This study shows that ins-11, an insulin peptide gene in C. elegans, is upregulated by different pathogens in specific tissues and influences immune responses and longevity.