Annemarthe G. van der Veen

This study identifies a noncanonical role for Dicer in regulating self-dsRNA sensing and innate immune responses to self-derived double-stranded RNA.

This study identifies USP24 as a novel ISG15 cross-reactive deubiquitinase that de-ISGylates MOV10 to negatively regulate IFN-I production.

This study shows Huwe1 is essential for RIG-I-like receptor-mediated type I and III IFN induction by ubiquitinating key pathway components like TRAF5.

This study shows that vault RNAs enhance viral replication by facilitating the nuclear export of ELAVL1 and hnRNP C, which are required for efficient viral replication.