Omid R. Faridani

The paper identifies cell-state-specific mechanisms of 5-azacytidine response in myelodysplastic neoplasms, showing distinct differentiation and transcriptional changes in cycling progenitors and quiescent stem cells.

The paper studies microRNA and target expression variation in mouse embryonic stem cells using genetic perturbation and single-cell RNA-seq, finding four co-expression groups and mixed effects on target variation.

Medlib provides a fast and feature-rich C/C++ library for exact alignment of Nanopore sequences using multiple edit distances, outperforming existing tools in speed and alignment completeness.

The paper predicts pregnancy outcomes in assisted reproduction by analyzing RNA from blastocoel fluid, showing higher RNA levels correlate with implantation failure.

The paper profiles small non-coding RNAs in multiple compartments of MS patients and controls, identifying distinct sncRNA expression patterns in CSF and PBMCs that suggest organ-specific regulatory mechanisms.

This paper introduces Smart-seq3, a single-cell RNA sequencing method that enables allele- and isoform-resolution RNA counting, showing improved sensitivity and isoform regulation detection in mouse and human samples.