Author

Jennifer E. Pogoriler

Children's Hospital of PhiladelphiaORCID 0000-0001-9366-4401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Amber K. WeineriD· 1 shared Andrew R. PetersoniD· 1 shared Anjali DhalliD· 1 shared Arnulfo MendozaiD· 1 shared Brigitte C. WidemanniD· 1 shared Cristina F. ContrerasiD· 1 shared Daiki TaniyamaiD· 1 shared Dan Martinez· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Amber K. WeinerORCID

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2 papers

Recent·Most cited

A Single-Cell Atlas of PVOD Across the Lifespan Reveals Cellular and Molecular Therapeutic Targets

Prashant Chandrasekaran, Sylvia N. Michki, Jennifer E. Pogoriler, Quinn Wright, MinQi Lu, Andrew R. Peterson, Hannah Hallquist, Edward Cantu, Edward E. Morrisey, Lisa R. Young, Maria Ciocca Basil, Susan M. Lin, David B. Frank

The paper constructs a single-cell atlas of PVOD across the lifespan, identifying endothelial dysfunction and molecular pathways as key drivers of the disease with potential therapeutic targets.

bioRxiv · Oct 14, 2026 · PreprintMolecular Biology

Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

Nai-Yun Sun, Suresh Kumar, Yoo Sun Kim, Diana Grace Varghese, Arnulfo Mendoza, Rosa Nguyen, Reona Okada, Karlyne M. Reilly, Brigitte C. Widemann, Yves G. Pommier, Fathi Elloumi, Anjali Dhall, Daiki Taniyama, Mayank Patel, Etan R. Aber, , Nitin Roper

This paper identifies DLK1 as a novel immunotherapeutic target in adrenocortical carcinoma, showing it regulates tumor cell plasticity and chemoresistance, and demonstrates the efficacy of a DLK1-targeting antibody-drug conjugate.

Nature Communications · Jul 1, 2025Peer-reviewedCancer Biology