Bernd Fischer

This study uses image-based profiling and multi-omics integration to identify morphological axes of variation in colorectal cancer organoids and link them to biological mechanisms and drug responses.

The paper shows that posttranscriptional regulation, specifically translational repression, controls the onset of differentiation in adult neural stem cells.

The paper investigates how RNA-binding proteins (RBPs) change in response to viral infection and identifies RBPs crucial for viral replication.