Qing Xu

The paper identifies enhancer-AAV tools for specific neuronal subtypes and validates them across species.

The paper analyzes transcriptomic differences in human brain cells with nine high-risk neuropsychiatric CNVs compared to non-carriers, finding widespread gene expression disruptions and shared functional pathways.

The paper identifies a conserved excitatory neuron gradient in human mediodorsal thalamus using single-nucleus and spatial transcriptomics, linking it to psychiatric disorder risk.

The paper shows pyramidal neurons influence the survival and identity of specific interneuron subtypes through non-synaptic mechanisms.

The paper shows that metabotropic signaling in somatostatin interneurons eliminates transient thalamocortical inputs during development, affecting adult exploratory behavior.

This study investigates neurogliaform cells in the visual cortex, showing their activity correlates with locomotion and their functional role is influenced by laminar position and connectivity.

This study shows that Nova proteins, through activity-dependent alternative splicing, are essential for the maturation and connectivity of somatostatin interneurons.

The paper identifies cell-type specific circuits formed by subtypes of somatostatin interneurons in the cortex through genetic targeting and connectivity analysis.

The paper maps presynaptic inputs to PV and SST cortical interneurons across cortical areas, revealing region-specific developmental patterns and differential vulnerability to neurodevelopmental disorders.

The paper shows that bottom-up thalamic inputs are essential for establishing top-down connectivity to layer 1 neurogliaform cells in the visual cortex during early development.

This study shows that stress-susceptible mice have blunted diurnal firing in LHb-DRN projections and slower photoentrainment, while resilient mice maintain normal rhythms and faster entrainment.

The paper uses deep RNA sequencing to compare gene expression in the subgenual anterior cingulate cortex across major psychiatric disorders and controls, finding disorder-specific expression changes and genetic associations.

The paper identifies enhancers for targeting specific neuronal subtypes across species and demonstrates their utility in circuit manipulation.