Peter C.M. van Zijl

Mitochondrial Oxidative Phosphorylation Capacity in Skeletal Muscle Measured by Ultrafast Z-Spectroscopy (UFZ) MRI at 3T

This study evaluates ultrafast Z-spectroscopy MRI with pH correction for measuring mitochondrial oxidative phosphorylation in human skeletal muscle.

Interrogation of dynamic glucose-enhanced MRI and fluorescence-based imaging reveals a perturbed glymphatic network in Huntington disease

This study uses MRI and fluorescence imaging to show impaired glymphatic function in a mouse model of Huntington disease, suggesting it as a potential biomarker and therapeutic target.

Concurrent measurement of perfusion parameters related to small blood and lymphatic vessels in the human brain using dynamic dual-spin-echo perfusion (DDSEP) MRI

This study introduces a new MRI technique to simultaneously measure perfusion parameters of small blood and lymphatic vessels in the human brain, showing faster signal changes in blood vessels than lymphatic ones.

Imaging meningeal inflammation in CNS autoimmunity identifies a therapeutic role for BTK inhibition

This study uses MRI to identify meningeal inflammation in a mouse model of multiple sclerosis and shows that BTK inhibition reduces inflammation.

HTT silencing delays onset and slows progression of Huntington disease like phenotype: Monitoring with a novel neurovascular biomarker

This study shows that HTT silencing in premanifest HD mice delays disease onset and slows progression, using CBVa as a noninvasive biomarker.

Heritability of regional brain volumes in large-scale neuroimaging and genetic studies

The paper examines the heritability of regional brain volumes using genetic and neuroimaging data from multiple cohorts, finding high heritability and consistent patterns across populations.