Robert C. Bauer

Single-Cell RNA-Seq Reveals Adventitial Fibroblast Alterations during Mouse Atherosclerosis

The paper uses scRNA-seq to study adventitial fibroblast changes in mouse atherosclerosis and identifies SERPINH1 as a key regulator affecting fibroblast function.

Depot-Specific Roles for C/EBPα in White Adipose Tissue Development and Metabolism

This study investigates the depot-specific roles of C/EBPα in white adipose tissue development and metabolism using Cebpa knockout mice, revealing distinct effects on gonadal and inguinal adipose depots and metabolic phenotypes.

Comprehensive Multimodal Profiling of Atherosclerosis Reveals Bhlhe40 as a Potential Regulator of Vascular Smooth Muscle Cell Phenotypic Modulation

Single-cell multimodal profiling of atherosclerosis identifies CD200 as a lineage marker of vascular smooth muscle cells and their derived cells

The paper identifies CD200 as a specific marker for vascular smooth muscle cells and their derived cells in atherosclerosis using CITE-seq and validates it across multiple techniques.

Decoding the Variant-to-Function Relationship for LIPA, a Risk Locus for CAD

The paper links LIPA risk alleles to increased monocyte/macrophage LIPA expression, which exacerbates atherosclerosis through enhanced PU.1 binding and altered macrophage function.

Genetic And Epigenetic Fine Mapping Of Complex Trait Associated Loci In The Human Liver

The paper fine-maps 77 GWAS loci in the human liver by integrating epigenetic and gene expression data to understand genetic and epigenetic regulation of gene expression.