Author

Mushtaq Ahmad Nengroo

Northwestern UniversityORCID 0000-0001-9775-4228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Austin T. Klein· 1 shared Daniel James McGrailiD· 1 shared Hardik ShahiD· 1 shared Heather S. Carr· 1 shared Issam Ben‐SahraiD· 1 shared John M. AsaraiD· 1 shared Marc L. MendilloiD· 1 shared Nidhi SahniiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Austin T. Klein

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1 paper

Recent·Most cited

Succinate dehydrogenase activity supports de novo purine synthesis

Mushtaq Ahmad Nengroo, Austin T. Klein, Heather S. Carr, Olivia Vidal-Cruchez, Umakant Sahu, Daniel James McGrail, Nidhi Sahni, Niklas B. Thompson, Peter Allen Faull, Peng Gao, John M. Asara, Hardik Shah, Marc L. Mendillo, Issam Ben‐Sahra

This study shows that succinate dehydrogenase supports de novo purine synthesis in cancer cells, and its inhibition reduces proliferation by impairing purine biosynthesis and inducing a compensatory salvage pathway.

Molecular Cell · Oct 28, 2025Peer-reviewedBiochemistry