Travis White

Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks

This study investigates LOH caused by CRISPR-Cas9 DSBs, showing large-scale loss and mechanisms, and highlights risks when combined with end joining inhibition.

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin

This study identifies the molecular mechanism by which FIGNL1 disassembles RAD51 filaments from DNA and chromatin, revealing its role in genome stability.

Genomic expression responses in sensu stricto Saccharomyces yeast to DNA damage induced by methyl methanesulfonate

The paper examines transcriptome responses to MMS-induced DNA damage in four Saccharomyces species, revealing species-specific gene expression changes and functional genomic insights.

Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex

This study identifies the SWS1-SWSAP1-SPIDR complex as a regulator of distinct homologous recombination pathways, with specific roles in inter-homolog HDR and cancer-related genomic instability.