Author

Serge N. Schiffmann

Université Libre de BruxellesORCID 0000-0002-0118-9816Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:electronic health records· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Marine Chazalon· 3 shared Alban de Kerchove d’ExaerdeiD· 2 shared Abeer Kaafarani· 1 shared Angelica Donati· 1 shared Anne Lefort· 1 shared Bert BrôneiD· 1 shared Bojana KokinoviciD· 1 shared Chadi Touma· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Marine Chazalon

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5 papers

Recent·Most cited

Synaptic Gpr85 influences cerebellar granule cells electrical properties and light-induced behavior.

Romain Darche-Gabinaud, Abeer Kaafarani, Marine Chazalon, Valérie Suain, Erika Hendrickx, Louise Conrard, Anne Lefort, Frédérick Libert, Mehmet Can Demirler, Serge N. Schiffmann, David L. Pérez-Morga, Valérie Wittamer, Marc Parmentier, Isabelle Pirson

This study identifies Gpr85 as a synaptically enriched modulator of neuronal excitability and light-induced behavior in zebrafish.

bioRxiv · Mar 10, 2025 · PreprintNeuroscience

Spontaneous activity of striatal projection neurons supports maturation of striatal inputs to substantia nigra dopaminergic neurons

Bojana Kokinovic, Patricia Seja, Angelica Donati, Maria Ryazantseva, Alban de Kerchove d’Exaerde, Serge N. Schiffmann, Tomi Taira, Svetlana M. Molchanova

The paper shows that spontaneous activity in striatal projection neurons is essential for the maturation and stabilization of their long-range projections to dopaminergic neurons.

bioRxiv · Jan 5, 2024 · PreprintNeuroscience

Lack of the glycine receptor alpha 2 increases striatal activity and motivated behavior

Jens Devoght, Joris Comhair, Giovanni Morelli, Jean‐Michel Rigo, Rudi D’Hooge, Chadi Touma, Rupert Palme, Ilse Dewachter, Martin vandeVen, Robert J. Harvey, Serge N. Schiffmann, Elisabeth Piccart, Bert Brône

This paper shows that lack of the glycine receptor alpha 2 in mice increases striatal activity and motivated behavior, linking it to psychiatric disorders like schizophrenia and addiction.

bioRxiv · Aug 31, 2022 · PreprintNeuroscience

mTOR-RhoA signalling impairments in direct striatal projection neurons induce altered behaviours and striatal physiology in mice

Daniel Rial, Emma Puighermanal, Marine Chazalon, Emmanuel Valjent, Serge N. Schiffmann, Alban de Kerchove d’Exaerde

This study shows that mTOR-RhoA signaling in direct striatal projection neurons affects behavior and striatal physiology in mice, with implications for treating mTOR-related disorders.

Biological Psychiatry · Jun 3, 2020Peer-reviewedNeuroscience

Induced pluripotent stem cell-derived primary proprioceptive neurons as Friedreich ataxia cell model

Chiara Dionisi, Myriam Rai, Marine Chazalon, Serge N. Schiffmann, Massimo Pandolfo

The paper describes a protocol to generate primary proprioceptive neurons from iPSCs and applies it to a Friedreich ataxia patient model.

bioRxiv · Nov 6, 2019 · PreprintNeuroscience