Author

Daniel John Renouf

BC Cancer AgencyORCID 0000-0002-7597-6089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Janessa J. LaskiniD· 3 shared Marco A. MarraiD· 3 shared Steven J.M. JonesiD· 3 shared David F. SchaefferiD· 2 shared Eleanor Lewis· 2 shared Eric Chuah· 2 shared Erin PleasanceiD· 2 shared Jessica NelsoniD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBioinformatics

Janessa J. LaskinORCID

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Author profile →

4 papers

Recent·Most cited

Endogenous insulin mediates dynamic coordination between pancreatic cancer and systemic metabolism

Jeffrey S.H. Lin, Aman A Mohammed, Keeley G. Hewton, Jingqiang Wang, Tiffany Z.Y Chen, Ivy S.Y Guo, Riley S.H Lam, Marcelo Ferraz Reinaldo, Vincent R. Richard, David F. Schaeffer, Daniel John Renouf, Christoph H. Borchers, Seth J. Parker, Josef Martin Penninger, James D. Johnson, Janel L. Kopp

This study shows that endogenous insulin in pancreatic cancer tumors affects tumor growth and systemic metabolism, with differential effects based on diet and mouse sex.

bioRxiv · Aug 27, 2026 · PreprintCancer Biology

Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours

Paul C. McDonald, James Thomas Topham, Shannon J. Awrey, Hossein Tavakoli, Rebekah Carroll, Wells S. Brown, Zachary J. Gerbec, Steve E. Kalloger, Joanna M. Karasinska, Patricia A. Tang, Rachel Anne Goodwin, Steven J.M. Jones, Janessa J. Laskin, Marco A. Marra, Gregg B. Morin, , Shoukat Dedhar

The paper identifies gene expression signatures related to neutrophil extracellular traps (NETs) in pancreatic ductal adenocarcinoma (PDAC) and shows they correlate with patient survival and metastasis, with potential therapeutic targets.

Communications Biology · Jul 4, 2025Peer-reviewedCancer Biology

Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities

Yuka Takemon, Erin Pleasance, Alessia Gagliardi, Christopher S. Hughes, Veronika Csizmók, Kathleen Wee, Diane L.N. Trinh, Ryan D. Huff, Andrew J. J. Mungall, Richard A. Moore, Eric Chuah, Karen Mungall, Eleanor Lewis, Jessica Nelson, Howard John Lim, , Marco A. Marra

bioRxiv · Jan 17, 2024 · PreprintBioinformatics

A Platform for Oncogenomic Reporting and Interpretation

Caralyn Reisle, Laura M. Williamson, Erin Pleasance, Anna Davies, Brayden Pellegrini, Dustin W. Bleile, Karen Mungall, Eric Chuah, Martin R. Jones, Yussanne P. Ma, Eleanor Lewis, Isaac Beckie, David Pham, Raphael Matiello Pletz, Amir Muhammadzadeh, , Steven J.M. Jones

PORI is an open-source platform for interpreting somatic variants in cancer, demonstrating that 88.2% of TCGA tumors have at least one potentially targetable alteration.

Nature Communications · Feb 9, 2022Peer-reviewedBioinformatics