Robert E. Guldberg

A Multi-Institution Biobanking Pipeline for Primary Human Satellite Cells and Fibro-Adipogenic Progenitors

This paper establishes a biobanking pipeline for primary human satellite cells and fibro-adipogenic progenitors, demonstrating their phenotypic stability and utility in muscle research.

Phased affinity-controlled delivery of vascular endothelial growth factor, fibroblast growth factor-2, and platelet derived growth factor enhances in vitro angiogenesis

This study develops affibody-conjugated hydrogels to phase the delivery of VEGF, FGF-2, and PDGF, enhancing in vitro angiogenesis by 2.8-fold in vascular network length and 4.1-fold in branching.

Mineralized collagen scaffold pore architecture and glycosaminoglycan content biases anti-inflammatory macrophage phenotype

This study shows how scaffold pore size, alignment, and glycosaminoglycan content influence macrophage polarization toward M2-like phenotypes in 3D mineralized collagen scaffolds.

Endogenous Osteocyte-Osteoclast Signaling Enables Bone Remodeling, Drug Response, and Cancer Invasion in a Nanoscale Calcified Bone-on-a-Chip Model

Melt Electrowritten Microfiber-Hydrogel Composite Scaffolds for Aligned Muscle Tissue Engineering

This paper develops a composite microfiber-hydrogel scaffold using melt-electrowriting to enhance muscle tissue engineering by improving mechanical strength, alignment, and myoblast differentiation.

Wireless Implantable Sensor For Non-Invasive, Longitudinal Quantification Of Axial Strain Across Rodent Long Bone Defects

This paper develops a wireless implantable sensor to measure axial strain in rodent bone defects, showing it can track mechanical cues during healing.