Natalie Charitakis

The DLX/Notch axis is necessary for spatiotemporal regulation of neural cell fate

The paper identifies a DLX2-regulated gene network that represses Notch signaling and glial fate factors to control neuronal-glial cell fate during forebrain development.

Application of spatial transcriptomics across organoids: a high-resolution spatial whole-transcriptome benchmarking dataset

This paper benchmarks spatial transcriptomics in stem cell-derived organoids using Stereo-seq, optimizing RNA capture and introducing regional analysis methods.

Maturation of human cardiac organoids are required for disease modelling and drug discovery

This study shows that maturing human cardiac organoids enhances disease modeling and drug discovery by mimicking in vivo development and enabling therapeutic testing for DSP cardiomyopathy.

Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods.

This study benchmarks spatial transcriptomics methods by comparing 6 SVG identification tools across 14 datasets, revealing discrepancies in results.

Automated Integration of Multi-Slice Spatial Transcriptomics Data in 2D and 3D

VR-Omics automates integration of multi-slice spatial transcriptomics data in 2D and 3D, revealing dysregulated metabolic networks in paediatric cardiac rhabdomyomas.

MonaGO: a novel Gene Ontology enrichment analysis visualisation system

MonaGO provides an interactive web-based visualization system for gene ontology enrichment analysis, offering dynamic clustering and customizable outputs to improve interpretation of results.

3D-Cardiomics: A spatial transcriptional atlas of the mammalian heart

This paper develops a 3D spatial transcriptomic atlas of the mouse heart and provides a web tool for analysis and visualization.