Author

Fraser Laing

Cancer Research UK

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Emily R. WebbiD· 3 shared Morwenna MuiriD· 3 shared Valerie G. BruntoniD· 3 shared A. R. S. BlackiD· 1 shared Ajitha RajaniD· 1 shared Alan SerrelsiD· 1 shared Alex von KriegsheimiD· 1 shared Alexander E.P. LoftusiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Emily R. WebbORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FAK Inhibition Remodels the Metastatic ECM and Restores CD8+ T Cell Trafficking and Immunosurveillance

Nicole D. Barth, Bo Peng, Michael Papanicolaou, Fatemeh Ahmadi Moughari, Camille L. Duran, Christopher S. McGinnis, John C. Dawson, Emily R. Webb, Morwenna Muir, Fraser Laing, Yookyung Jung, Xue‐Yan He, Ansuman T. Satpathy, Mikala Egeblad, Syed Aleem Haider, , Valerie G. Brunton

This paper shows that FAK inhibition remodels the metastatic ECM, enhancing CD8+ T cell infiltration and immunosurveillance in breast cancer.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology

FAK inhibitor treatment systemically regulates the glioblastoma immune environment via blocking monocyte trafficking

Emily R. Webb, A. R. S. Black, Giovana Carrasco, Muhammad Furqan, Robert L. Hollis, Alexander E.P. Loftus, Joel A Ochoa, Romain Enjalbert, Tara Best, Xiaozhong Peng, Morwenna Muir, Fraser Laing, Martin W. Lee, Sofian Al Shboul, Tongjie Wang, , Valerie G. Brunton

This study shows that systemic FAK inhibition reduces immunosuppressive macrophages in glioblastoma by blocking monocyte trafficking, enhancing T cell activity and improving survival in a mouse model.

bioRxiv · Nov 26, 2025 · PreprintImmunology

USP18 Inhibition Enhances Type I Interferon Signalling and Immune Activation in the Tumour Microenvironment of Triple-Negative Breast Cancer

Chartinun Chutoe, Emily R. Webb, Morwenna Muir, Fraser Laing, Valerie G. Brunton, Alex von Kriegsheim

This study shows that inhibiting USP18 enhances type I interferon signaling and immune activation in TNBC, converting immunologically cold tumors into hot ones and improving immunotherapy efficacy.

bioRxiv · Sep 1, 2025 · PreprintCancer Biology